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Regressive ASD Linked to Temporal Lobe Activity

By Chelsea E. Toledo, M.A. on September 1, 2015
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Background: The temporal lobe, one of the four major parts of the brain’s cerebral cortex, aids in processing sound, categorizing objects, and consolidating memories. It also plays a role in visual processing, emotions, and language. Researchers first began to suspect a relationship between temporal lobe abnormalities and autism spectrum disorder (ASD) in 1975. (see second Pubmed link below)


What’s New: On July 30, 2015, the journal European Child & Adolescent Psychiatry published a study investigating if irregular electrical brain activity – an indicator of epilepsy – could predict any specific feature of ASD. The researchers analyzed the results of brain scans from 220 children and young adults, 71 with ASD and 146 with other developmental disorders. After performing brain measurements on a subgroup of participants, they found a correlation between abnormal electrical brain activity, relatively large head size, and loss of previously acquired developmental skills, known as regression. The relationship between regression and abnormal electrical brain activity was the strongest when that activity took place in the temporal lobe.


Why it’s important: The results of this study support the possibility that irregular electrical activity in distinct brain areas may predict or help define ASD subgroups.

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