Risk Factors

The diuretic drug bumetanide has shown promise in preliminary studies as a therapy for children with autism. Now an animal study using bumetanide sheds light on autism’s underlying mechanism, linking both genetic and environmental risk factors to oxytocin’s effect on brain changes during birth. Please explore the Risk Factor section of Autism Reading room to learn more about genetic and environmental influences on autism.


In the Risk Factors Section, you will learn about:

Autism Spectrum Disorder (ASD) can be caused by multiple conditions, called risk factors,that have been linked to an increased likelihood of developing ASD. Risk factors can be genetic or environmental.

Genetic risk factors relate to inborn problems in our DNA, such as a gene deletion or duplication. Genetic risk factors are present at birth.

Environmental risk factors, however, stem from social, physical, or chemical exposures and can be present during fetal development or months to years after birth.

In the Risk Factors section of the Autism Reading Room, scientific experts discuss the interaction between environment and genetic risk factors as well as misconceptions about the causes of ASD.