Rett Syndrome Diagnosis

To be diagnosed with Rett Syndrome, a patient must have all of the following:

  • Apparently normal prenatal and perinatal development
  • Apparently normal psychomotor development through the first 5 months after birth
  • Normal head circumference at birth
  • Deceleration of heath growth between ages 5 and 48 months
  • Loss of previously acquired hand skills between 5 and 30 months of age, with the subsequent development of stereotyped hand movements
  • Early loss of social engagement
  • Poorly coordinated gait or trunk movements
  • Severly impaired expressive and receptive language development with severe psychomotor retardation

Adapted from the Diagnostic and Statistical Manual of Mental Disorders, Fourth EditionĀ (DSM-IV).